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An additional challenge is represented by climate change, as it will force coastal communities to apply more or less drastic adaptation strategies.
Detailed phylogenetic analysis allows formulation of a hypothesis for the evolution of the TAM: Although TamB was already present from the earliest-branching Phyla, TamA is the result of a gene duplication of BamA followed by drastic adaptation or partial sequence exchange of two POTRA domains, resulting in the TAM complex exemplified today in E. coli.
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Although Kinsley finds it ridiculous, Mulder believes that centuries of seclusion could be adequate for such drastic adaptations to happen.
Alexander Pope said Cibber's drastic adaptations and patchwork plays were stolen from "crucified Molière" and "hapless Shakespeare".
Monogynous mating systems with extremely low male mating rates have several independent evolutionary origins and are associated with drastic adaptations involving self-sacrifice, one-shot genitalia, genital damage, and termination of spermatogenesis immediately after maturation.
We conclude that stress conditions have a major impact on the transcript expression and therefore confirm that these RNAs could be implicated in gene regulation and bacterial adaptation to drastic environmental changes.
Hence, the high concentration and the central metabolic position make expression levels of glycolytic enzymes susceptible to drastic changes during physiological adaptations or pathological alterations, such those occurring in several myopathies [26] and in disuse-induced muscle atrophy [27], [28], in which a strong rearrangement of AQP4 expression is also found.
This is a reasonable assumption, given that global or gene-specific translational regulation of gene expression is a mechanism that allows fast adaptations during drastic changes in environmental conditions as well as during rapid transitions in developmental programs.
The opposite is also a potential adaptation, to increase adaptability to more drastic environmental changes and in life-history.
If average selection intensities are very weak, as suggested by some studies, even modest changes in the effective population size between species may have drastic impacts on rates of adaptation between lineages.
Consequently, we call "pro-adaptation" as the ability to rapidly adapt to drastic environmental changes by an appropriate reaction norm which increases genetic variability and "pro-adaptors" as the genetic modulators of this reaction norm.
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