Sentence examples for drastic accumulation from inspiring English sources

Analysis of sphingolipids and glycosphingolipds in cells treated with the glycosides showed that the α-anomer caused a drastic accumulation of ceramide and glucosylceramide and reduction of lactosylceramide and GM3 ganglioside at concentrations above a threshold of 20 μM.

Profiling analyses of UV-active metabolites in the rice calli and seeds expressing the OASA1D transgene also demonstrated that drastic accumulation of tryptophan had little effects on the profiles of other UV-active metabolites except for the accumulation of a few minor indole alkaloids in these tissues [72, 100].

Inhibition of PS/γ-secretase by using pharmacological and genetic approaches induces a drastic accumulation of neurexin C-terminal fragments (CTFs) in cultured rat hippocampal neurons and mouse brain.

In contrast treatment of Mz-ChA-1 and TFK-1 cells resulted in drastic accumulation in the G2- phase.

In this experimental model of obstructive hepatic injury, damage was induced by ligature of the common bile duct leading to a drastic accumulation of collagen content in the liver.

This drastic accumulation of PINK1 then serves to recruit Parkin, which ubiquitylates the outer membrane protein(s) of mitochondria with no membrane potential with the ubiquitylated mitochondria destined for final degradation in part via mitophagy (Narendra et al. 2008, 2010; Geisler et al. 2010; Matsuda et al. 2010; Vives-Bauza et al. 2010; Ziviani et al. 2010).

Treatment for 18 hrs with U18666A mimics the Niemann Pick type C phenotype [34], [54], [55] showing a drastic cholesterol accumulation in late endosomes (Fig. 3CF and 4CF).

Therefore, the drastic starch accumulation during turion formation marks a turning point in the switch process from low-starch fronds to high-starch turions.

Similarly, the rice sugary-1 (null for isoamylase) and the maize dull-1 (not expressing SSIII) mutants had drastic changes in accumulation of pullulanase and SBEIIb isoforms, respectively [ 43, 44].

The essential role of AgamOBP1 in the perception of indole was ultimately demonstrated in this study by the EAG responses of A. gambiae females subjected to AgamOBP1-dsRNA injections, which caused a drastic reduction in AgamOBP1 accumulation.

cSMAC formation was also impaired, because the same conjugates displayed a drastic reduction in the accumulation of Lck and PKC-θ at the cSMAC.