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Foxp3 mRNA levels were dramatically upregulated during iTreg differentiation, as expected.
The human LITAF domain protein, SIMPLE, has been hypothesized to be involved in the regulation of PCD since it is dramatically upregulated during p53-mediated apoptosis [22], [26].
However, miR-4732-5p levels were less dramatically upregulated during erythropoiesis.
However, since H3K23me3 becomes dramatically upregulated during early meiosis, we proceeded to analyze ΔEZL3 cells for meiotic phenotypes.
The expression of these adhesion molecules is low in healthy CNS ECs, but can be dramatically upregulated during injury and disease.
miR-1 and miR-133a are dramatically upregulated during the differentiation of cardiac and skeletal muscle (Chen et al., 2005; Ivey et al., 2008).
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The expression of these subunits is dramatically upregulated by Stat3 during involution and this is associated with a decrease in the levels of pAkt.
Prochlorophytes, such as the marine phytoplankton Prochlorococcus, do not have a unique iron-stress antennae protein, but their normal protein (PcbB) closely resembles IsiA and is dramatically upregulated in some species during iron stress to form enlarged ring structures around PSI akin to the IsiA supercomplex [44].
For example, L1-like retrotransposon that encodes ORF1 and ORF2 is dramatically upregulated in the blastema during axolotl (Ambystoma mexicanum) limb regeneration [ 155].
We have shown that Akt1 is dramatically upregulated at both the mRNA and protein levels during lactation [ 25, 90] and have previously described the lactation failure that occurs in transgenic mice expressing constitutively activated myr-Akt1 in the mammary gland [ 25].
For example, Survivin is normally only expressed during mitosis in adult cells, but is dramatically upregulated in many cancers leading to a poor prognosis for recurrence-free survival [ 11- 13].
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CEO of Professional Science Editing for Scientists @ prosciediting.com