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In other words, by not conditioning on known affected sibling status, the prediction model will dramatically under-estimate the absolute risks.
It has previously been shown that physicians dramatically under-estimate the potential for these therapies to cause side effects and interact with conventional medications [ 10].
A former high ranking cyber-security expert with the British government told the meeting that the cost of online crime was being dramatically under-estimated.
They under-estimated her.
And often, she under-estimated herself.
"People under-estimate the importance of handwashing.
Unlike HS2, though, there's a possibility nuclear fusion could come in dramatically under-budget.
In print, radio and television media, female newsmakers are dramatically under-represented.
Here's how dramatically estimated payments might change: A married couple filing jointly with 2008 taxable income of $600,000, who pay only through estimated taxes (meaning they don't have regular jobs with withholding) will owe New York state $18,300 in estimated taxes come June 15, instead of the $11,300 they would have owed under the old law, calculates Berkowitz.
Under Shekau's leadership, the group's operational capability and tempo has increased dramatically, and an estimated 5,000 people have been killed in the period since. .
Never under-estimate under-promisers.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com