Exact(2)
Hairy cell leukemia [HCL] is a rare B cell malignancy that is dramatically responsive to DNA damaging chemotherapy.
It is dramatically responsive to corticosteroid treatment, but symptoms and radiopacities recur frequently after tapering or discontinuing the medication.
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Even on relatively low-powered devices like Nokia's budget-conscious Lumia 610, Windows Phone doesn't feel dramatically less responsive than it does on more robust hardware (though there are a few limitations in place).
But this deadly naïvete was quickly reversible: Female moose whose calves were killed by wolves were dramatically more responsive to wolf calls, the team reports in the 9 February issue of Science.
In this preclinical study, we have demonstrated clearly that intra-tumoural, extra-cellular pH changes dramatically in response to two different chemotherapy regimens in responsive tumours.
Using the well established type 2 diabetic animal model db/db mice, we observed a dramatically enhanced LA responsive mitochondrial Ca2+ efflux and protein nitrotyrosylation in the kidney.
In their clinical study, since Spry4 levels were dramatically decreased in patients responsive to the drug compared with non-responsive patients, the authors proposed Spry4 as a reliable marker of the imatinib-responsive treatment.
The therapeutic efficiency of loaded drugs can be dramatically improved using redox-responsive nanoplatforms which can sense the differences in the redox status of tumor tissues and healthy ones.
In summary, we treated a patient with recurrent TCH apparently triggered by micturition without any underlying organic causes, which was responsive to nimodipine dramatically.
We here disclose that IG1 contains a calcium responsive enhancer which dramatically triggers the activity of the PADI3 gene promoter located 86-kb from it upon epidermal keratinocyte differentiation, and links PADI3 expression to AP-1 transcription factors through chromatin opening and looping.
The number of responsive transcripts increased dramatically from 12 to 32 dpi in both cultivars, but in contrast, in T200 the levels did not change significantly at 67 dpi, while in TME3 they declined.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com