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A late development in the betting on this year's Nobel prize in literature has seen a "dramatic" shortening of odds on an outsider, the Norwegian author and dramatist Jon Fosse, while Japanese novelist Haruki Murakami continued as favourite to win the prize.
"It's a very dramatic shortening of the potential pathways".
Given that validated surrogate endpoints allow dramatic shortening of clinical trials, with associated savings and a faster availability of new treatments, this is an area in which both the pharmaceutical industry and the healthcare authorities are pushing for biomarker use.
Given that validated surrogate endpoints allow dramatic shortening of clinical trials by shortening the time to the study end point, with associated savings and a faster availability of new treatments, this is an area in which both the pharmaceutical industry and healthcare authorities are pushing for biomarker use.
Therefore, the observed dramatic shortening of the measured decay time at elevated temperature implies thermal activation of non-radiative carrier recombination, consistent with the results of cw-PL measurements (Figure 2). Figure 3 Decays of the integrated PL intensity measured from the GaP/GaNP NWs at 5 K and RT.
There was dramatic shortening of villi in the small intestine.
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This dramatic loss of cells was correlated with a striking shortening of the gut (reduced by 40%) and an increase in gut width.
This suggests that dramatic telomere shortening can accelerate cell senescence.
In budding yeast, TEL1 deletion results in dramatic telomere shortening and activation of telomere recombination events [ 156].
Moreover, an elegant study by Chen et al. (2013) has recently reported dramatic period shortening (≈2 hr) of free-running rhythms in miRNA-deficient mouse embryonic fibroblasts (MEFs), likely caused by the lack of three miRNAs (miR-24, miR-29a, miR-30a) targeting Per1 and Per2 mRNAs.
The authors found that dramatic life-shortening effects are observed among female rats, particularly in those where LL-treatment was started at one month of age.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com