Compared with the jp (jimpy) mouse, which has much more oligodendrocyte death and hardly any myelin, microglia in the overexpressors show a more dramatic microglial reactivity than jp, especially in the grey matter.
Synthetic models that incorporate different axial ligand or distal metal are inspired by the design of heme proteins in nature where these modifications at the heme site are associated with dramatic changes in reactivity.
The Pd-BnM/formate combination, as previously discussed for kinetic experiments, exhibited a dramatic loss in reactivity when applied to the COPR leachate compared to model Cr VI) solutions.
Increasing amounts of GdnHCl yielded dramatic increases in 3F4 reactivity for all strains (Fig. 3B), consistent with previous reports that this region undergoes a major conformational change upon conversion of PrPC to PrPSc [22] [24].
The MEM264 epitope overlaps with an area in the peptide binding region predicted to undergo a large global movement upon peptide release, and previous results [16] and those shown here demonstrate a dramatic difference in the reactivity of this antibody for peptide-loaded and peptide-free DR1.
Efforts to re-engineer BcII through mutagenesis have shown similar variability in the position of Zn2, with dramatic effects on the reactivity of the resulting enzymes.
The dramatic differences in nitrite reactivities of the Lucina Hbs are not related to their O₂ affinities or anaerobic redox potentials, which were found to be similar, but are instead a result of differences in accessibility of nitrite to their active sites; i.e. these differences are due to a kinetic rather than thermodynamic effect.
The agglomeration behavior and surface charge variation of nanoparticle dispersions can have a dramatic effect on both the reactivity of nanomaterials and their efficiency in contamination treatment [7, 25, 26].
However, this difference in the ratio of reactivity is less dramatic when considering reactivity with histidine and lysine residues.
The reactivity differential was especially dramatic at the latter stages of the polymerization.
