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In particular, work with the dystonic (dt) rat has engendered dramatic paradigm shifts in dystonia research.
It is a body of knowledge determined by history and ever-changing intellectual fashions, so that even the most widely accepted beliefs about science are subject to dramatic paradigm shifts.
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Complexity based on simple rules characterizes the dramatic paradigm shift from mass production to customization.
This paradox necessitates the conclusion that MTAs exert mitosis-independent effects, spurring a dramatic paradigm shift in our understanding of the mode of action of MTAs.
Re "The Heart Grows Smarter" (column, Nov. 6): Bravo to David Brooks for bringing attention to the dramatic paradigm shift that is happening in our culture and in our science.
There was no dramatic paradigm shift, since both had considerable support and all working biologists would have been familiar with them.
A dramatic paradigm shift toward controlled ontologies is needed in order to optimize the technologies that integrate big data into medical decision making and practice.
In recent years, novel molecular-targeted agents have been developed based on the precise understanding of molecular mechanisms underlying the progression of RCC, and the introduction of these new drugs has induced a dramatic paradigm shift in the therapeutic strategy for metastatic RCC (Bellmunt et al, 2007; Lane et al, 2007).
In comparison with the WSSD, which was largely concerned with implementation rather than with new visions, treaties and agreements, Rio led to a dramatic new paradigm shift in thinking on sustainable development, and to new legally binding agreements such as those concerned with biodiversity, and with climate change.
Big paradigm shifts have taken centuries.
And in that moment a paradigm shifts.
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CEO of Professional Science Editing for Scientists @ prosciediting.com