"dramatic paradigm shift" is correct and can be used in written English.
It is typically used to describe a major change in how something is thought of or done. For example, "The rise of digital technology has brought about a dramatic paradigm shift in how people communicate."
Re "The Heart Grows Smarter" (column, Nov. 6): Bravo to David Brooks for bringing attention to the dramatic paradigm shift that is happening in our culture and in our science.
Complexity based on simple rules characterizes the dramatic paradigm shift from mass production to customization.
This paradox necessitates the conclusion that MTAs exert mitosis-independent effects, spurring a dramatic paradigm shift in our understanding of the mode of action of MTAs.
There was no dramatic paradigm shift, since both had considerable support and all working biologists would have been familiar with them.
A dramatic paradigm shift toward controlled ontologies is needed in order to optimize the technologies that integrate big data into medical decision making and practice.
In recent years, novel molecular-targeted agents have been developed based on the precise understanding of molecular mechanisms underlying the progression of RCC, and the introduction of these new drugs has induced a dramatic paradigm shift in the therapeutic strategy for metastatic RCC (Bellmunt et al, 2007; Lane et al, 2007).
In particular, work with the dystonic (dt) rat has engendered dramatic paradigm shifts in dystonia research.
In comparison with the WSSD, which was largely concerned with implementation rather than with new visions, treaties and agreements, Rio led to a dramatic new paradigm shift in thinking on sustainable development, and to new legally binding agreements such as those concerned with biodiversity, and with climate change.
You need a paradigm shift.
Talk about a paradigm shift.
