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This elegant monograph traces "dramatic mutations" in the concept from Jesus to Augustine, along with changing ideas about time, the cosmos, the devil, divine justice, and the human body.
Using new statistical methods, they have found many less dramatic mutations that, for example, also help highland Tibetans survive at high altitude.
p.Gly162Asp is one of the most dramatic mutations we identified because it introduces a negative residue inside the hydrophobic core.
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His mid-1970s analysis of a dramatic mutation occurring within contemporary societies and rise of a new mode of simulation, which sketched out the effects of media and information on society as a whole, is also original and important.
One dramatic mutation, I53D, results in the conversion from a three-state to a two-state folding mechanism, which is explained most easily through a simple destabilization of the kinetic intermediate such that it is no longer stable with respect to the unfolded state.
As a lived tradition, Islam is constantly undergoing dramatic mutation.
The loss on mutation was much more dramatic for mutations according to PAM120 (yellow in Fig. 3C) than for those according to the background distribution (green in Fig. 3C).
My suggestion is that the sudden expansion of the brain 200,000 years ago was a dramatic spontaneous mutation in the brain of Mitochondrial Eve or a relative which then spread through the species.
Whole genome duplication (WGD), or polyploidization is a rare, but dramatic genetic mutation event which doubles the size of a genome and creates a redundant pair of copies from every gene.
For example, Endicott and Ho [ 4, 12] observed dramatic differences in mutation rates, mutation saturation, and selective effects in different partitions (e.g., first, second and third codons, D-loop, rRNA) of human mitochondrial genomes; similar findings have been reported by Ingman and collaborators [ 13], also in humans, and by Subramanian et al. [ 5] in Adélie penguins (Pygoscelis adeliae).
The differences are even more dramatic when dominant mutations are sought.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com