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Serious clinical complications frequently arise due to dramatic modification of the structural and functional properties of P. falciparum-infected erythrocytes (IEs) [1].
This impairment, characterized by a generalized immune activation and a CD4 T-cell depletion has, as consequence among others, a dramatic modification of cytokine and chemokine profiles [22], [23].
Thus, these results have clearly evidenced that the benefit of the multidrug nanoassemblies resulted from a dramatic modification of the pharmacokinetic and biodistribution profiles of the two biologically active compounds, in comparison to their administration just as free drugs.
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The deposition of quartz as pore-filling cement and/or veins is a common diagenetic process during burial sedimentation, and can cause dramatic modifications of bulk-rock mechanics, including changes in stiffness (Laubach et al. 2004), consolidation behavior (Karig and Morgan 1994), and frictional properties (Lockner and Byerlee 1986).
The three bidimensional spectroelectrochemistry signals have demonstrated the occurrence of different types of degradation processes depending on the applied potential, ranging from the simple release of oligomers and hydrolysis products retained in the film during electropolymerization to more dramatic modifications of the film.
Personality in this sense can be lost, what we experience, for instance, in the dramatic modifications of the identity of persons during the pathological processes of frontotemporal dementia or Alzheimer disease [ 46].
Thus, detecting "adaptive decay" may require more dramatic modifications to the environment.
The organization of the anthocyanin inclusions present in BMS35S::R+35S::cellslls undergo dramatic modifications in the presence of light.
Resident duty-hour regulatory changes in July 2011 led to dramatic modifications in the structure of many surgical training programs in the United States.
The more than 300 currently identified post-translational modifications (PTMs) provides great scope for subtle or dramatic alteration of protein structure and function.
These algorithms cannot be directly applied to this domain because most of them lead to several dramatic modifications such as light condition changes, color temperature alterations, and additional artifacts introduced or amplified.
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CEO of Professional Science Editing for Scientists @ prosciediting.com