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Perhaps the most dramatic hypothesis is that low vitamin D levels may be a factor in multiple sclerosis, the devastating degenerative neurological condition.
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To test our hypothesis of dramatic gene loss we performed analysis of the genome regions which are orthologous between Genlisea and Mimulus.
We thus assessed PDI puncta formation following ISG15 overexpression and in line with our hypothesis found a dramatic increase in puncta formed upon ISG15 expression.
In testing this hypothesis, we discovered dramatic upregulation of GPI-anchored glypican Dlp and transmembrane Sdc HSPGs at dfmr1 null NMJ synapses.
An alternative hypothesis is that dramatic changes in chromosome number appear as a consequence of a within-species accumulation of numerous chromosomal rearrangements, resulting in highly polymorphic systems with the subsequent extinction of intermediate karyomorphs.
The present result supports, from the aspect of historical repeatability, the famous (but never evaluated) evolutionary hypothesis that the dramatic labroid radiations in trophic ecology are due to evolution of specialized pharyngeal jaw apparatus (PJA).
Based on the previous literature, here we tested the ecological hypothesis that the dramatic variation in plant Taxol content may be caused by underlying variation in its Taxol-producing fungal endophytes acting as elicitors of enzymes in the plant Taxol biosynthetic pathway.
Oceanic islands offer many opportunities for understanding the patterns and processes of organic evolution, and they provide dramatic settings for testing the hypotheses of evolution and biogeography (Emerson, 2002).
In support of this hypothesis, we detected a dramatic increase in Aire expression in both spermatocytes and spermatids (Fig. 3B and C).
Furthermore, as predicted by the hypothesis, PII had a dramatic effect on the glutamine Kact of the reconstituted enzyme, almost exactly as obtained with the wild-type enzyme.
The weak response to indomethacin and the dramatic improvement after verapamil therapy supported this hypothesis.
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