Sentence examples for dramatic changes in sequence from inspiring English sources
Our observations are consistent with the previous demonstration that mutation of one or a few residues in the NHR RH can result in dramatic changes in sequence preferences, but that mutations elsewhere in the DBD play a role in sequence selectivity (e.g., McKeown et al., 2014).
After incorporating Azo-py into the 4A loop position of an i-motif sequence, dramatic changes in fluorescence occurred as the DNA structures changed from single-strands to i-motif quadruplex structures.
Analysis of the immunostimulatory profiles of these IMOs in human and NHP cell-based assays suggest that changes in the number of synthetic immunostimulatory motifs gave only a subtle change in immune stimulation of pDCs as indicated by IFN-α production and pDC maturation while the addition of self-complementary sequences produced more dramatic changes in both pDC and B cell stimulation.
In nearly 55% of 101 experimentally well-annotated enzyme superfamilies (accounting for almost 50% of all enzyme sequences in CATH-Gene3D) dramatichangeses in catalytic machinery occur [ 39].
As a consequence, relatively minor changes in sequence or folding conditions can result in dramatic changes in kinetic behaviour [ 28,29].
In contrast to the dramatic changes in the number of qualified spectra, the percentage of qualified spectra that were correctly sequenced hardly changed across the datasets and the values of N (Fig. 6b).
Dramatic changes in diet and physical activity.
