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This skepticism was further increased by the accumulation of negative human trials of immunomodulatory drugs that had previously shown dramatic benefits in experimental studies (Table 1).
As he noted to me, colleagues in Germany have already seen dramatic benefits in seven depressed treatment-resistant volunteers in the first experimental trial, six of whom showed clear increases in appetitive motivation with markedly diminished depression.
Recent studies demonstrate a reduction in mortality, beside dramatic benefits in comorbidities, in obese patients treated surgically.
While response rates were modest and of limited duration, implementation of trastuzumab in concert with chemotherapy provided dramatic benefits in the adjuvant setting [ 3, 19].
This skepticism was further increased by the accumulation of negative human trials of immunomodulatory drugs that had previously shown dramatic benefits in experimental studies (Table 1).
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Those who watched the video scored higher on all areas of memory assessment when compared to those who did not see the video; they also experienced a dramatic benefit in cortisol levels.
The test of the hypothesis that 17-α-estradiol might improve health in males thus gives equivocal results—a dramatic benefit in males at one site but no significant benefits at the other two sites.
On the contrary, EGFR mutations were associated with a dramatic benefit in terms of PFS in both placebo-controlled (Brugger et al, 2009) and chemotherapy-controlled trials (Fukuoka et al, 2009; Douillard et al, 2010).
There were also musical-dramatic benefits in having the work sung by so small a group.
Cell therapy has received much attention for its potential to regenerate ischemic organs, but initial clinical trials in aged patients did not replicate the dramatic benefits recorded in preclinical studies with young animals.
But a new analysis of a long-term study in Jamaica shows that surprisingly simple ways of stimulating children's mental development can have dramatic benefits later in life.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com