Sentence examples for dramatic activation from inspiring English sources

Furthermore, MC-LR caused a concentration-dependent decrease in the activity of protein phosphatase 2A (PP2and andramaticactivationatiof of p38 mitogen-activated protein kinase (MAPK).

The reporter assay showed a dramatic activation of ERE-promoter activity by 17β-estradiol (~25-fold).

Interestingly, the simultaneous cotransfection of CREBH and HNF4 α caused a dramatic activation of APOA5 promoter activity, compared to that when either factor alone was cotransfected).

Consistently with these findings, apoptosis assessed by caspase 3 activity showed a dramatic activation in ARO/CD133neg in comparison to ARO/CD133pos cells at all time points analyzed (Figure 6A, representative of three independent experiments with doxorubicin).

This finding may reflect more dramatic activation of the type I IFN pathway at sites of active inflammation in the target tissue.

Our study demonstrates dramatic activation of Akt-1 by VLPs, with moderate upregulation of the protein.

For this reason, at the anti-inflammation stage cells need to make use of the negative regulator proteins and cytokines to inhibit the function of some dominant cross-talks to recover from the dramatic activations in inflammation.

Transcript profiling of tumors showed that virus infection resulted in a dramatic transcriptional activation of pro-inflammatory genes including the neutrophil chemoattractants CXCL1 and CXCL5.

ROS reportedly induce dramatic Src activation.

When small neurons started undergoing apoptosis at month 2 (Supporting Fig. S1), dramatic co-activation of WOX1 (>65% of cells), CREB (>65%) and NF-κB (40 65%) occurred in the small neurons of both non-injured and injured sides (Fig. 4).

The soma of the RGC "senses" that its axon has been injured within 30 min. This interpretation of our data is based on the dramatic de-activation of the phosphorylation state of ERK1 in the Muller cells within 30 min. Muller cells and astrocytes express activated ERK-1 in the retina, and these cells express higher levels in retinas from glaucomatous donors [ 24].