All authors contributed to the drafting and completion of the manuscript.
Both authors have contributed equally to the design, data collection, data analysis, drafting and completion of this article.
All the authors contributed equally to the design, data collection, data analysis, drafting and completion of this article.
JJ carried out the microalgae and biomass production and harvesting, anaerobic cultivations and all related analyses, microbial community analyses, data interpretation, and drafting and completion of the manuscript.
AML carried out the anaerobic cultivations and all related analyses, microbial community analyses, data interpretation, and drafting and completion of the manuscript.
Editorial assistance with the drafting and completion of the manuscript was provided by Daniel Booth (Bioscript Stirling, London, UK) and funded by Janssen Cilag EMEA.
JL coordinated collection of materials and performed pretreatment at pilot scale and small scale, fractionation and hydrolysis experiments, statistical analysis, data interpretation, and drafting and completion of the manuscript.
TR made a considerable contribution to the collection of the data, analysis and interpretation, drafting, revising and completion and final approval of the manuscript.
Patient and orthodontist questionnaires were drafted and completed at the beginning, during, and on completion of treatment.
QY, YJW, CCL, CKS carried out fossil processing, photography, figure preparation, data analysis and interpretation, drafting of manuscript and completion of study.
