Sentence examples for downstream stress from inspiring English sources

Exact(12)

Eight DEGs, including transcription factors, kinase, and downstream stress responsive genes, showed a tissue- and time-dependent differences in their expression.

Not surprisingly, CDPKs were primarily recognized as signaling mediators, which perceive rapid intracellular changes of Ca2+ ion concentration, for example triggered by environmental stress cues, and relay them into specific phosphorylation events to induce further downstream stress responses.

The properties of this mutant are consistent with a model whereby stress signals are linked to downstream stress tolerance responses that are modulated by RNA processing.

However, there is limited knowledge about mechanisms underlying the conversion from oxidative signaling to downstream stress events leading cells to death.

Because both H-ras and ASK1 have been shown to activate p38 MAPK during times of growth and stress, respectively, we anticipate that H-ras mediathe the phosphorylation of p38 MAPK to promote migration and proliferation of the fibroblast, while ASK1 phosphorylates p38 MAPK to activate downstream stress responses.

Given the lack of knowledge of aging-induced changes in adiposity and leptin signaling, the precise interplay between aging and obesity, and contribution of leptin signaling and downstream stress signaling activation, if any, to the cardiac contractile dysfunction in the state of concurrent aging and obesity warrant further research.

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Similar(48)

They play a key role in the regulation of expression of downstream stress-responsive genes in ABA signalling.

The network of post-transcriptional and post-translational modifications ensures temporally and spatially appropriate patterns of downstream stress-related gene expression.

They can bind to the cis-acting element in promoters of their target genes and regulate expression of downstream stress-responsive genes in drought and salt stress signal transduction (Zhu 2002; Yamaguchi-Shinozaki and Shinozaki 2006).

ABA stimulates expression of transcriptional activators such as ABF/AREB transcription factors, which are responsible for activating expression of downstream stress-responsive genes in ABA-dependent stress signalling (Zhu 2002; Yamaguchi-Shinozaki and Shinozaki 2006).

In this respect, TFs are important in regulating the expression of downstream stress-regulated genes [53].

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