Sentence examples for downstream significance from inspiring English sources

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To a more limited extent the Report's recommendations on prioritizing projects in view of potential downstream significance are also in line with our recommendation to insist on an implementation plan for all basic research, tying them more closely to applied research [ 31].

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The downstream functional significance of the β2-M/HFE complex is depicted in Figure  7.

Genes that were represented by good quality spots on a minimum of three replicate slides were considered for downstream analysis using SAM (significance analysis of microarray) to identify differentially expressed genes.

Genes were chosen for downstream analysis based on significance (P < 0.05, FDR-corrected).

This is because each change of the filters influences the downstream false discovery rate significance calculation.

We remark that if one was to use the concept of MTB to identify one set of reliable miRNA-target modules for downstream analyses, the statistical significance of such modules should be carefully corrected taking into account the number of hypothesis tests performed.

We downloaded GWAS data compiled by the National Human Genome Research Institute [ 44]: this included 256 diseases and traits, and 2,298 gene loci harboring potentially associated SNPs (mapping inter-genic SNPs to the nearest upstream and downstream genes at a significance threshold P < 10-5; see Table S1 in Additional file 1 and Figure S2 in Additional file 3 for disease/trait distribution).

Bonferroni correction was used to adjust the significance level S1 downstream, S2 midstream, S3 upstream.

Other tools are used in downstream analyses to understand the significance of the identified SNPs.

We have developed a novel algorithm to evaluate the statistical significance of direct downstream target genes for a TF.

Locus tag, Name of TF, Size and FDR q-val represent the gene ID, the corresponding regulator gene, the number of regulated downstream genes and the statistical significance, respectively.

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