Sentence examples for downstream regulation from inspiring English sources

It was therefore of interest to find gene categories performing specific meiotic functions that lie further downstream (regulation of meiotic transcription, meiosis I and meiotic chromosome segregation) among the up-regulated genes.

Moreover, the molecular mechanisms of upstream and downstream regulation of Slug are largely unknown.

ADARB1 encodes an RNA editing enzyme, expressed mainly in the central nervous system (CNS), which is involved in the downstream regulation of neurotransmitters [22].

In addition, cells are dynamic systems with complex regulatory networks that activate cascades of downstream regulation that is sensitive to type and frequency of incoming stimulus.

Regulated genes were associated with biological functions using previously published literature reports and various databases, in addition to upstream and downstream regulation analysis and canonical pathway analysis generated by Ingenuity Pathway Analysis (IPA) software.

The assays also suggested that compound 24 is an Hsp90 inhibitor, and that the Akt/mTOR pathway might be involved in the downstream regulation that leads to its antiproliferative activity.

However, their states are determined regardless of other elements once the state of Mevalonic acid is given, thus such later downstream regulations are not as specific to the presence of statins.

The dependent downstream-regulation cascade can be controlled by PPARG itself or by PPARG in combination with the controlling factor C/EBPA (also up-regulated in our study).

These data are consistent with the hypothesis that ligand binding regulates heterodimer choice and downstream gene regulation by these nuclear receptors.

These results presented here will provide novel insight into the downstream signaling regulation of the chitin and PGN immune responses in rice.

Because Yki is the important link between Wts and downstream transcriptional regulation of Hpo signaling [13], we examined the expression pattern of Cut and Hnt in yki overexpressing clones.