Sentence examples for downstream program from inspiring English sources
The Wnt signaling downstream program is poorly understood, and a very useful downstream gene specific for this pathway is Axin 2, which upon transcription and translation, acts as a negative feedback regulator of the Wnt siginaling pathway, by helping direct β-catenin for degradation in the proteasome [3], [4].
This in turn, results in translational repression and the activation of downstream programs that can limit cell growth through cell cycle arrest and/or apoptosis.
The hard wired KEGG pathways and interconnections between them define how BMP6 signal triggers downstream programs.
Finally, two types of output (dual synteny plot and circle plot) were obtained by using two downstream programs.
By evening and her upteenth cup of tea she'll be on the phone with UNICEF Headquarters in New York to discuss downstream programs and fundraising gaps.
Downstream programs impact cell cycle progression, apoptosis, proliferation and angiogenesis among others, and through these mechanisms, contribute to hematopoiesis and human cancers.
Recommendation 2: In light of the needs for child protection support at multiple levels in Thailand, UNICEF Thailand should consider the need for both upstream and downstream programming approaches.
Our pipeline uses Velvet-Oases and Trinity for the initial assembly and constructs a meta-assembly with CAP3 followed by analysis with various downstream programs, including BLAST and Blast2GO [ 26– 29].
One central component of this pathway is the cytoplasmic protein β-catenin, which when translocated into the nucleus as a result of Wnt signals, serves as a co-factor for transcription factors of the Lef-1/Tcf (Lymphoid enhancer factor-1/T Cell Factor) family to allow for activation of a downstream genetic program [11].
Released cytochrome c enables the formation of the apoptosome, which in turn initiates the downstream caspase program [ 10].
To test this, we compared the ability of Ngn3 and AcNgn3KO to drive a downstream transcriptional program in vivo, in Xenopus embryos.
