The phrase 'downstream players' is correct and usable in written English.
This phrase is usually used to refer to those in an organization who interact with customers, or to those who benefit from the decisions made by higher-level business leaders. For example, "The marketing team is a key downstream player that keeps customers engaged and coming back."
The implications for other downstream players will be mixed.
All of the farm-preneurs were aware of the upstream and downstream players, as well as the related risks and opportunities.
Most other downstream players in the car-related industries will have to adapt to new technology but will not be existentially threatened.
Through the ability to better parse and make use of this data, the idea is that these downstream players can then facilitate significant improvements in patient care, treatment and, really, basic understanding of how the body works via insights at the molecular level.
Taken together, these studies suggest that the Twist1 family might be the key downstream players in heart hypertrophy/dilation induced by abnormal Akt signaling (enhancement or reduction).
The differential analysis of multiprotein complexes containing variants of PrPC that are permissive or refractory to cleavage may lead the identification of the relevant sheddases and possibly also of downstream players involved in prion toxicity.
We find that the AbdB-Boss/Sev cascade affects integrin independent of Talin, while genetic interactions depict integrin as the central downstream player in this system.
An important downstream player in the effects of metabolic flexibility is the mitochondrion.
To accomplish this, we inhibited non-muscle myosin II, which is a downstream player in the Rho/ROCK pathway and an important component of stress fiber formation.
The E2 enzyme Ubc4 is upstream of Ufd2 in the ubiquitination process of proteins targeted to proteasome (Jentsch et al., 1990; Sommer and Seufert, 1992) whereas Rad23 and Dsk2 are Ufd2-downstream players bridging ubiquitinated proteins to the proteasome (Chen and Madura, 2002; Funakoshi et al., 2002; Kim et al., 2004).
The downstream molecular players that permit Mit mutants and their defective mitochondria to increase lifespan remain, however, largely unresolved.
