Sentence examples for downstream outcome from inspiring English sources

Studies suggest that early ventilator settings influence downstream outcome of critically ill patients [34].

Instead, we were concerned with the downstream outcome of chemotherapy treatment that could concurrently inhibit HIF- α and activate the p53 pathway.

Biochemically, the signaling state of a protein can be examined in the absence of such reagents directly by antibody immunoprecipitation of the protein followed by an in vitro kinase assay with substrate and radioactively labeled ATP or indirectly by transfection with a reporter construct that measures a downstream outcome of kinase activation such as ERK activation of AP-1.

Studies that evaluate the linkages between watershed improvement through Best Management Practices (BMPs) and downstream outcomes are few.

This egalitarian approach to diminishing researcher views may have also meant down-grading, and eventually eliminating, researchers' focus on predictive models and downstream outcomes.

We also revealed two important downstream outcomes: whereas the lower strain judgments associated with a stress-is-enhancing mindset led to a higher estimate of the target's promotability, they also led to a lower likelihood of helping him.

Data from whole-animal tests of the downstream outcomes would not be required for risk assessment of these outcomes.

The effect of treatment choice on downstream outcomes such as recurrence and risk of death is not well understood.

The overexpression of this phosphatase is reported to cause diverse downstream outcomes, such as cell cycle progression, apoptosis, differentiation, and migration.

How should changes in upstream indicators within "normal" ranges be considered in evaluating potential for overt downstream outcomes in susceptible individuals and populations?

(ii) The flexibility of IDRs also allows for easy access and recognition of the PTMs within the IDR by effector proteins that mediate downstream outcomes upon binding.