Sentence examples for downstream of the normal from inspiring English sources

Null mutations in Slbp result in incorrectly processed histone mRNAs, due to read through and utilization of cryptic polyadenylation sites downstream of the normal cleavage site [27], [28], [29].

The WT-147-3′ivs WT-147-3′ivs WT-147-3′ivsy inserting a 147 bp fragment in an AvrII site loconstructediately dowastream of the normal stop codon in a derivative of WT-3′ivs; the AvrII site was introduced by PCR.

Finally, in the modified TH2 response, downstream effects of the normal TH2 responses are muted and result in an increase of noncomplement fixing IgG4 and IL-10 [ 16, 33, 34].

Pancreatic islets from Nnt knockout (NntKO) mice have a normal response to the potassium channel blocker tolbutamide, implying that the regulation of insulin secretion downstream of the KATP channel is normal.

Downstream of the incident site (d), normal capacity is assumed to be restored and vehicles can accelerate away so the traffic conditions eventually return to normality, although the initial high density of traffic can lead to reduced speed persisting over many kilometres.

Demonstrating receptor activation can involve detecting phosphorylation of intracellular signaling-pathway proteins known to operate downstream of the activated receptor in normal, responsive cells.

The new method is verified for a number of test cases at Mach 10, including the one-dimensional high-temperature flow downstream of a normal shock, a hypersonic chemical reacting boundary layer in local thermodynamic equilibrium and a hypersonic reacting boundary layer with finite-rate chemistry.

Moreover, in some instances, the artificial insertion of an intron downstream of a normal stop codon can make it behave like a PTC (Carter et al, 1996; Thermann et al, 1998); similar observations were also reported in plants (Kerenyi et al, 2008).

In contrast, RhoG is essential for normal granule secretion downstream of the collagen receptor GPVI.

The ability to treat kinase-active and kinase-impaired CFC embryos suggests correction of signalling downstream of the CFC mutation is sufficient to restore normal development.

This leads to restoration of the normal physiological HIF pathway and reduction of accumulation of HIF-1α and downstream hypoxia response element related transcription.