Sentence examples for downstream of the initial from inspiring English sources

However, retention of intron 1 introduces a UAA stop codon 123 bp downstream of the initial AUG.

Because HMMSplicer must match the second piece of the read downstream of the initial exon edge identified, the HMMSplicer algorithm is sensitive to maximum intron size.

Decreased activity of ISRE and SRF was observed after the initial time point, suggesting these TFs respond downstream of the initial stimulation.

To reduce search space to a manageable and biologically relevant size, a default of 80 kbp downstream of the initial alignment is considered, although the user may adjust this to the most appropriate value for the organism and experiment.

This suggested that a significant component of the cytokine polarization of responses to iNKT cell activating glycolipids in vivo depends on the extent to which IFNγ and potentially other proinflammatory cytokines are produced by other leukocytes that undergo transactivation downstream of the initial iNKT cell stimulation.

The ability of SIRT1 activators to prevent neuronal loss in both models therefore suggests they modulate a common mechanism of neurodegeneration downstream of the initial mechanisms of injury.

To analyse the downstream fate of the initial labelling products, 13C partitioning into the glucose, glucose-6-phosphate (G6P) and sucrose pools was monitored.

The genomic instability observed in tumor cells and all other recognized hallmarks of cancer are considered downstream epiphenomena of the initial disturbance of cellular energy metabolism.

Relatively little is known about the economic burden of chemotherapy-induced FN in European and Australian clinical practice, however, and no studies conducted outside the US have considered the burden of care for the initial FN event as well as the downstream consequences of the initial event.

Furthermore, in all the 409 cases classified, the downstream gene had alternative start codons which were downstream of the predicted initial codon, which could produce a product with a similar or even an equal length to its orthologs.

Current dogma suggests that RA signaling is the primary step in establishing the intermediate mesoderm, thus putting lhx1 directly downstream of this initial pattering event [10], [13], [58].