Sentence examples for downstream net from inspiring English sources

For continuous PTH dosing, the model predicts a desensitized system dominated by the inactive receptor and complex, consistent with downstream net bone loss that has been demonstrated experimentally.

Therefore, we directly measured the activity of E2F transcription factor as the "executive" protein reponse to inhibition of miR-17, -20a, and -106b and thereby record their downstream "net" effect on E2F activity caused by the interplay of their pro- and anti-proliferative targets.

All of the genetic-metabolic abnormalities that are being revealed to underlie the mysteries of glioblastomas lie upstream but their downstream net effects can be quantified by the model.

Watershed-scale monitoring, field aeration experiments, and geochemical equilibrium and kinetic modeling were conducted to evaluate interdependent changes in pH, dissolved CO2, O2, and Fe(II) concentrations that typically take place downstream of net-alkaline, circumneutral coal-mine drainage (CMD) outfalls and during aerobic treatment of such CMD.

It should also be emphasised that model parameters D and ρ are net, downstream from any intracellular metabolic activity controlling migration and proliferation, irrespective also of any microenvironmental factors that might further modify them.

Upstream and downstream primers of NET-1 0.5 μl (10 pmol/μl) were designed (NET-1-S: 5′-GTGGCTTCACCAACTATACG-3′, NET-1-AS: 5′-GACTGCATTAGTTCGGATGT-3′).All reactions were performed in a 25 μl volume with 150 nM primers, 0.25 units of Amp Erase Uracil- N-glycosylase and 1× SYBR Green PCR Master Mix Applied BiosystemsSYBR Green PCR Master Mix Applied Biosystems

The response coefficients of maltopentaose with respect to enzymes catalyzing these other reactions are small, as expected for net flux "downstream" and rate limitation "upstream".

A few kilometres downstream, boys fish with nets.

Somatostatin receptor signalling pathways can promote a wide range of downstream effects in GEP-NETs including inhibition of cell secretion and growth through the modulation of mitogen-activated protein kinase (MAPK) signalling or induction of apoptosis (Patel and Srikant, 1997).

Upstream reaches are net erosional, while downstream reaches have a distinctly net depositional flux providing a watershed sediment balance of 2184 kg/m/y trapped within the system.

This phenomenon might be explained by the β-carotene produced by increased synthesis being rapidly transformed into downstream compounds, resulting in a net decrease in β-carotene content.