Sentence examples for downstream interplay from inspiring English sources

Our results begin to reveal the downstream interplay of the signaling events brought about by the activation of each of the two receptors, indicating the biological effect of receptor/ligand specificity.

One aspect of Ni2+/Co2+ dependent regulation of PknJ can be the downstream substrate phosphorylation while interplay between kinase and metal sensor or their activating enzymes is also possible.

Here we present a first kinetic model on platelet signaling including time-resolved interplay and downstream effects of cyclic nucleotide signaling pathways.

Further deciphering of the complexities of breast cancer signal transduction pathways, their regulation and interplay, including elucidating downstream gene effects, is important, not least because therapeutic resistance is a persistent problem for all therapies targeting known pathways.

The problem, researchers concluded, lay downstream of that processing, in the interplay among higher-level processing regions of the brain.

Our work provides first evidence that the PUF motif is enriched around predicted miRNA binding, offering the possibility for functionally relevant localization of the PUF binding site downstream the miRNA sites for the interplay between the two systems.

These results support the essential role of DNA methylation in the plasticity of the hematopoietic system [27], [28], suggesting interplay between transcription factors downstream of cytokine receptors and the DNA methylation machinery.

These data also suggest the interplay between p53, its downstream effectors, and Aurora-A.

We show in turn that suppression of IGF-IR by the use of a tyrosine kinase inhibitor and siRNA technology can promote erbB3 downstream signalling by reinforcement of erbB3 interplay with IRS-1.

Due to the complex interplay of regulatory interactions, these downstream genes are unstable.

Given that mTORC1 regulates ribosome biogenesis through the downstream substrate P70S6K, there may be an interplay between the two mTOR complexes.