Sentence examples for downstream contributors from inspiring English sources

Anti-ecdysteroidal compounds may act by reducing ecdysteroids titers, competing antagonistically for the ecdysteroids receptor, or modulating the availability or activity of downstream contributors to the signaling cascade.

It is entirely possible that histamine-induced inflammation is an early and/or downstream contributor in AD.

Because sites in the lower right quadrant have high concentrations of nutrients and low processing they are major nutrient contributors to downstream waters.

However, downstream effectors and/or or parallel contributors other than a deregulated Hox-program are required for leukaemia development [11], [41].

Of several signaling pathways frequently deregulated in HCC, the canonical Wnt pathway, with β-catenin as a crucial downstream component, is an important contributor to tumorigenesis (Farazi and DePinho, 2006).

In the prediction of overall SOC, Rrs was the major predictor in the upstream and downstream portions, whereas soil texture was the major contributor in the midstream portion.

Excess nitrogen (N) export from lowland artificial watersheds (polders) is often assumed to be a major contributor to the cultural eutrophication of downstream aquatic ecosystems.

The contraceptive estrogen, ethinylestradiol (EE2) is an important contributor to the feminization of fish downstream from sewage treatment works [ 1- 5].

The results suggest that periodic downstream drying-up of the river is the largest contributor to the induced ecological impacts in terms of emergy cost.

Smad proteins, transcription factors downstream of TGF- β/BMP, positively regulate cardiac fibrosis, a major contributor to adult heart disease and functional impairment by regulating the expression of distinct extracellular matrix (ECM) proteins (reviewed in [ 56]).

Since LC3 lipidation is downstream of Atg5, it is unlikely LC3 will be a main contributor of the observed changes in Ca2+ signaling.