Sentence examples for downstream candidates from inspiring English sources

GESearch was not only limited to coexpression analysis [ 36] but also useful for identifying the downstream candidates.

For representatives of downstream candidates, the most highly co-expressed P450 and glycosyltransferase transcripts identified in the co-expression analysis were also included in the collection.

Finally, we screened the downstream candidates of MF signaling as the mutual DEGs in response to both the short-day condition and MF treatment.

dsRNA was injected into female pupae (RNA-seq) or adults (downstream candidates) at 32°C using the following concentrations: arrow, 2.1 µg/µl; frizzled1/2, 2.3 µg/µl; hh, 2.0 µg/µl; orthodenticle, 2.4 µg/µl; torso, 2.3 µg/µl; wntless, 2.1 µg/µl and >2 µg/µl for downstream candidates.

The potential downstream candidates responsible for this phenotype are genes involved in the regulation of proliferation and/or self-renewal pathways [ 24, 53], and loss of p73 leads to a transcriptional deregulation of Sox-2, Sox-3, Nanog, Notch-I, Notch-2, Hes-5, Jag2, Hey-2 and Deltex.

Among these downstream candidate genes, we were able to establish that Tcl1 is a new direct target gene of Oct3/4, based on several lines of evidence: promoter activity assays by luciferase reporter in Oct3/4-cotransfected fibroblast cells and ES cells; direct binding by in vitro EMSA assay; and in vivo binding assay by ChIP.

This difference served as a standard for real-time PCR detection for downstream candidate gene selection [ 42].

Its downstream candidate targets included Ddit3, which is known to induce cell death under endoplasmic reticulum stress.

Upon electrical stimulation, MEK1 and its downstream candidate, extracellular signal-regulated protein kinases 1 and 2 (ERK1/2), were activated only in LMNAR225X/WT dermal fibroblasts, but not in control fibroblasts.

Sequences encompassing 100 nt upstream and downstream candidate SECIS elements identified by the covariance model were translated in full (including stop codons) using the EMBOSS transeq program and assuming UGA→U decoding.

Since in some imprinted clusters more than a single gene met this condition, we grouped all physically consecutive candidate cluster center genes to a single gene which start site was defined as the start site of the most upstream candidate center gene and end site was defined as the end site of the most downstream candidate center gene.