Sentence examples for downstream activity from inspiring English sources

After binding IGF ligand, IGF-1R undergoes autophosphorylation, inducing various substrate activations and downstream activity.

Signalling continues through AKT, DOCK1 and RAS to sustain RAC1/CDC42 activity, which result in the downstream activity of p21 protein (CDC42/RAC -activated kinases (PAKs), mitogen-aCDC42/RAC -activatedses (Mkinases finally activation of JNK/PAKs

The RhoGTPase-activating domain in Myo9b inhibits Rho, reducing the downstream activity of ROCK (RhoKinase), thereby increasing MLC phosphatase activity, reducing MLC phosphorylation (Reinhard et al., 1995, Wirth et al., 1996), and, therefore, reducing actin stress fiber formation.

Rac downstream activity, which counteracts the RHOA-ROCK axis,32 was blocked by the PAK inhibitor IPA3.

These extra meanings are typically loosely formulated, in which case it is not possible to validate the feature-based model to ensure that it provides a correct representation for a downstream activity such as process planning.

If you are an integrated oil company, this downstream activity nicely balances out the drilling cycle.

These results support previous reports that have shown that LPS induces activation of NF-kB and downstream activities in normal or osteoarthritic mammalian chondrocytes [ 47- 54].

Evidence suggests that different conformational forms of GPRs allows downstream activities to be specifically modulated based on the individual ligand that binds and activates the receptor (Table 2).

"Both the upstream and downstream activities surprised with better than expected profits".

He might have added that divisions among upstream and downstream activities are evaporating too.

Just under half of this amount will need to go into primary agriculture, and the rest into food processing, transportation, storage and other downstream activities.