Sentence examples for downstream action from inspiring English sources

Each block both the production of and the downstream action of the critical intermediate granulocyte-macrophage colony-stimulating factor.

The IRS protein cascades are the common elements in the peripheral response and signaling pathway since these protein cascades are recognized by others in the signaling pathway for further downstream action.

These members are involved in the downstream action by cisplatin.

Inhibition of the downstream action of these angiogenic receptors has been shown to induce endothelial cell apoptosis [ 9, 20].

This action should include an "upstream" approach that tackles the social and cultural determinants of the disease supplemented by "downstream" action focusing on oral health promotion [ 38].

A benefit in developing imaging agents targeting over-expressed receptors is that the downstream action of the targeted receptor need not correspond to specific tumorigenesis mechanisms.

These finding suggests that there are downstream actions upon which the proliferativc action of these drugs depends.

Immediately downstream, actions of the ERG24p (C-14 sterol reductase) together with ERG25p, ERG26p, and ERG27p result in the synthesis of zymosterol, the substrate for the C-24 sterol methyltransferase, ERG6p.

We have shown previously that reactive stroma promotes prostate cancer progression via induction of angiogenesis and the downstream actions of TGF-β1 induced factors in reactive stroma including connective tissue growth factor (CTGF) and fibroblast growth factor 2 (FGF-2) [18] [19], [19].

RhoGTPases control diverse downstream actions through distinct effector proteins.

The pathogenesis of DPN is fundamentally mediated by hyperglycemia and/or insulin deficiency and their associated downstream actions.