Sentence examples for downregulated upon from inspiring English sources

Western blot analysis indicates Polycomb group (PcG) proteins, SUZ12, EZH2, RING1B and BMI1, are downregulated upon KDM2B knockdown, but they are not the direct downstream of KDM2B.

These differentially expressed genes (DEGs) mainly included MYB, NAC, TIFY and Zn-finger TFs, and most genes were downregulated upon submergence.

The expression analysis revealed that entire clusters of genes were either up- or downregulated upon combination of fibroblasts and keratinocytes in cultured skin grafts.

Gene expression profiling in Wnt3A and lithium-exposed hMSCs showed that many osteogenic and chondrogenic markers, normally expressed in proliferating hMSCs, are downregulated upon Wnt stimulation.

Our results demonstrate that L1TD1 mRNA is rapidly downregulated upon EB formation (Figure 1A).

Therefore our data suggests that L1TD1 mRNA is rapidly downregulated upon hESC differentiation.

Gene expression profiling revealed that 14% of the polyadenylated maternal transcripts were downregulated upon aging.

Interestingly, we found that GPC1 is downregulated upon PRDM5 expression in U2OS cells.

However, mRNA and protein levels of p53 and its effecter p21 were downregulated upon BMI-1 knockdown (data not shown).

Although HDACis have been known to induce gene expression, an equal number of genes are downregulated upon HDAC inhibition.

Furthermore, we provided evidence that the L1TD1 protein expression is also downregulated upon hESC differentiation in multiple hESC cell lines.