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Although it is possible for the classification of agents to change over time in either direction, in practice there have been rather few instances of agents being "downgraded" between successive periods.
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Egypt has expelled Turkey's ambassador and downgraded relations between the two countries, a day after the Turkish Prime Minister Recep Tayyip Erdogan called for the release of ousted president Mohammed Morsi.
Hurricane warnings were downgraded to gale warnings between High Island, Texas and Freeport, Texas between the late afternoon of August 9 and the late afternoon of August 10.
Susa's claims are somewhat dented, however, by the fact that it was downgraded to "small settlement" between the 15th and 20th centuries.
Q: Has cannabis always been in class B? A: It was downgraded to class C between 2004 and 2009 by the Blair government following warnings the classification lacked credibility.
It was downgraded to Class C between 2004 and 2009 but upgraded again due to concerns about the impact of stronger strains on users' mental health.
Later that morning, hurricane warnings were downgraded to tropical storm warnings between Indian Pass and Destin as well as between Anna Maria Island and the Suwannee River while all remaining warnings were dropped south of Anna Maria Island, as well as the Florida east coast and the Georgia coast.
Considered less free than countries such as Mozambique, Mali and Panama, America's rating has been downgraded thanks to growing tension between the administration and the media caused, for example, by pressure on reporters to reveal sources.
This comparison is summarized in Summary of findings 4. The evidence of no difference between antimicrobials was downgraded to low quality due to concerns about the risk of bias of the studies and their age, with the most recent study being 25 years old.
Only last week Moody's said it saw differences between Ireland and Portugal when it downgraded the latter's debt to junk status.
Relations between the countries were downgraded to the lowest level short of a break in 2011 after protesters in Tehran attacked the British Embassy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com