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The swapped segments are so large that it takes many generations before they are whittled down to a length too small to be recognized.
The recent finding that Ubp2 can efficiently and preferentially deubiquitinate K63 linked chains [24] suggests a possible role for Ubp2 in editing Rsp5-catalyzed polyubiquitin chains down to a length suitable for recognition by various proteins in the endocytic/ESCRT machinery.
Imaging by atomic force microscopy (AFM; supplementary Fig S4 online) revealed the surface of the film to be flat, indicating that the film is laterally homogeneous, at least, down to a length scale of a few 10 nm.
The X-ray unit (DEN S-O-MAT; Gendex, Milan, Italy) was set at 70 kV and 7 mA with exposure time of 0.06 ms. After the radiographic examination, the samples were trimmed down to a length of 30 mm, which contained the entire distracted region.
Cut the elastic down to a length that is suitable for the snake's tongue.
Carefully trim the wire down to a length of 3/16 inch (5 mm) before inserting it into the hole with flatnose pliers.
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Gottlieb describes the difficulty he had in cutting it down to a marketable length: It took a year.
That typically involves a director accumulating a dozen hours of footage (through multiple takes, shooting scenes from different angles, and so on) and then editing it down to a reasonable length.
It was heartbreaking to cut it down to a manageable length".
The original screenplay was written by Sidney Howard, but underwent many revisions by several writers in an attempt to get it down to a suitable length.
We applied Nielsen et al.'s CLR using HapMap2 genotype data, and for chr4:158Mb, it detected a signal of selection localized to ~40 kb, while for the chr10 22Mb region, where the HapMap2 SNP density was high in the critical interval, the selected region was narrowed down to a similar length to the sequencing data (Fig. 4).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com