Sentence examples for down the functional from inspiring English sources

Understanding the origins of these variations may provide valuable insights in tracking down the functional variants in genomic regions identified by genetic association studies.

The neat thing is we are starting to break down the functional walls and the functional silos that we have had historically as a company.

The work "pushes the field in novel ways, Akey adds, as very few studies have pinned down the functional consequences of genetic changes that have been selected for.

We then truncated Bud3p-NM to narrow down the functional region.

In this article, we'll look at a handful of farsighted companies including Eli Lilly, Bank of America, and Dow Chemical that have broken down the functional silos to develop a process that we call succession management.

To identify the common target genes for miR-638, we narrowed down the functional pathway enrichment analysis using two different algorithms.

A similar reciprocal regulation was observed for Lipopolysaccharide-induced TNF factor (LITAF) in KKv1 knock-down (si KKv1) versus the knock-down of the functional parent gene KLK4 (si KLK4wt).

Most striking was the distinctively pronounced reciprocal regulation of Interleukin 8 (in8) in BG knock-down (si BG) versus the knock-down of the functional parent gene GATM (si GATMwt).

This knock-down affected the functional capacity of TEC to adhere to laminin, the specific ligand of integrin receptors containing α6 subunit, in addition to a loss of the typical stellate profile.

Several investigations have shown a functional role for ADAMS in collagen deposition in cells and in lungs in which the ADAM gene was knocked down, thus revealing the functional dysregulation of this gene family in the lung fibrosis [ 53- 55].

Granzyme A and TNF decoy receptor tnfrsf6b, which were also down-regulated by the functional feeds, showed strongest correlation with heart histopathology level in a previous CMS study [ 11].