Intriguingly, this notion of destabilization has also been put forward in the experimental study of Pina et al. (2012), who observe that early exit of HSPCs from the self-renewal state is not yet linked with specific gene expression changes that would commit the cell to differentiate down a single trajectory.
When Jesse Palmer throws the ball, running back Tiki Barber said, it arrives with the tip tilted down slightly, a trajectory that gives it a heavier feel.
Talent, ambition and heavy promotion raised him up; self-delusion, denial, drugs, racism, and gay panic brought him down: a very American trajectory.
But in Tuesday's workout, Clemens seemed to find the magic slot, and his splitter dropped and dived straight down, a much different trajectory from his two-seam fastball.
"He didn't seem on a trajectory to buckle down for A-levels and a place at university," said a housemate.
Off he goes, down the slide at a trajectory that will probably hit the glass, ice, and stone blocks in exact order, resulting in a flawless kill.
The army's active-duty force levels, known as "end strength", ought to return to 540,000 soldiers, where they were earlier in the decade, reversing a trajectory heading down to 450,000 by 2018.
For many patients, in particular the elderly, a hospitalization may be a turning point with regard to cognition, with a down-ward trajectory in the years following [ 10].
– FG1#1 In addition to a fear of needles and injection practice itself, the youth mentioned a further fear of addiction which they saw as a down-hill trajectory, which almost inevitably followed the transition into IDU: "I just wouldn't do that [IDU] cause that's how people get really bad…I don't want to end up on East Hastings… I want better for myself than that".
"This indicates that these parts continued in a down and forward trajectory before breaking up".
The leaking of select names on the list of players who tested positive for steroid use in 2003 included his name first and foremost, and it dragged down the trajectory of his phenomenal accomplishments.
