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A randomized trial of the protocol in community health clinics showed a doubling of testing among the intervention sites [24].
Based on the trial of Hickman et al., we assumed a current testing rate of 8%, estimated a coefficient of variation of 0.8 and aimed to demonstrate a doubling of testing to 16% post-intervention, with an excess of 95% power to detect such a change, given a 1% significance level.
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However, the number of lattices was doubled to test the grid dependency results.
ELISpot assay results were defined as positive when there was a statistically significant difference (p = < 0.05) between the average of the sfc in test and negative control wells (Student's two tailed t-test), plus at least a doubling of sfc in test compared with control wells, plus a difference of at least 10 sfc between test and control wells.
Our data show that the triple combination was highly synergistic against drug-resistant viruses, and the synergy of the triple combination was significantly greater than the synergy of any double combination tested (P<0.05), including the combination of two NAIs.
Furthermore, the synergy of the TCAD regimen was greater than the synergy of any double combination tested for all three 2009 H1N1 strains.
Studying combinations of double mutants, further tested the function of Rols, Loner and other fusion molecules.
In 1955, the inventor of the double-blind design form of testing, Henry K Beecher, discovered that 35% of patients found satisfactory relief from a placebo.
USDA had announced it was doubling its testing of these cows; it had been testing about 20,000 downers in order to be able to detect one case per million cattle.
He has also earned praise for his zero tolerance approach to doping, doubling the number of tests at the Games to 5,000 and introducing more rigorous out of competition tests and target testing.
Each of the above viruses was diluted to 100 50% tissue culture infective dose (TCID50)/well, mixed with doubling serial dilutions of test serum beginning at 1 5 (giving the first serum dilution 1 10), and incubated for 1 h at 37°C.
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