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Prior studies comparing the chest radiograph with EVLW measured using the thermodilution method used double indicator methods to measure the amount of EVLW [12, 14 17].
The measurement of extravascular lung water index by double indicator (EVLWIdi or the measurement of extravascular lung water index by transpulmonary thermodilution (EVLWItt) could be useful after pneumonectomy.
We evaluated the less invasive arterial double indicator dilution method (TDD) as an alternative.
All these patients were hemodynamically monitored by the transpulmonary double indicator (thermo-dye) dilution technique.
Double indicator dilution, which is the most accurate method of EVLW measurement, is no longer commercially available.
EVLW was assessed by the transpulmonary double indicator technique with intravenous injections of ice-cold indocyanine green (ICG).
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Individual feed intake was estimated using the alkane double-indicator technique.
Accordingly, an experimental study previously showed that pleural effusion in dogs had no effect on the values of EVLWI measured by double-indicator dilution technique [66].
We found an FDG extraction fraction of 18%, which is in line with earlier reported values of approximately 20%[35]], determined using the double-indicator method [36].
In the same pig model, our study group found comparable changes of filling volumes when investigating the influence of an IAP of 30 mmHg over 24 h using the double-indicator dilution technique [25].
PBV can be determined using double-indicator TPTD technique [ 13].
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