The punctate staining in this region, wherein a single dot occasionally resolves into double foci, is a hallmark of rhoptry localization.
Indeed, the number of γH2AX foci, which is a hallmark for double strand break formation, was reported to be increased by exposure to B[a]P [ 11].
DNA double-strand breaks, another hallmark of apoptosis, assessed by the TUNEL assay, were detected in Huh-7 cells after treatment.
Genome analysis indicates that Acd1 is closely similar to other Sulfolobales and likely has the characteristic S-layer membrane [ 34], distinct from the unique double membrane that is a hallmark feature of Ignicoccus[ 41], genus so far exclusively marine.
A substantial number of cells in the neocortex of Nde1−/−Lis1+/− and Nde1−/− mutants showed abnormally high γH2AX immunosignals, a hallmark for DNA double strand breaks (DSBs) (Thiriet and Hayes, 2005; Figure 1A).
The Yankees managed only four singles and a double and used small-ball hallmarks like the stolen base and the sacrifice fly.
Produced about 1800, it was probably made for use at a wedding, judging from the calligraphy emblazoning the back, which delivers the Hallmark-like message "double happiness" and is circled by images of five bats, signifying good fortune.
MSF, which operates and supports a number of health centres and field hospitals in Syria, said the attack bore the hallmark of a double-tap strike, whereby the first bombing is followed by a second one after paramedics have arrived to help the victims.
On the other hand, γ-H2AX is considered to be a hallmark of DNA double-strand breaks (DSB) [43], and Western blotting was therefore performed using ant-γ-H2AX ant-γ-H2AX ant-γ-H2AXbilito of 5-aza-Cdruleduced DSB.
Antinuclear autoantibodies (ANA) and especially autoantibodies against dsDNA (double stranded DNA) represent a serological hallmark of SLE, and may serve as indicators for disease activity and severity [ 6, 7].
