That a TMS double-pulse can generate a performance decrement for stimuli presented far outside of the retinotopic region directly affected by the TMS, is most certainly an indication of a non-specific bias, e.g. due to the auditory or somato-sensory distractions accompanying the pulses.
This analysis suggests that a doubling in mercury concentration produces a decrement of approximately 10% of a standard deviation, or 1.5 IQ points.
The odds of driving cessation doubled with each 5 decibel (dB) decrement in the better-eye VF mean deviation (MD) (OR = 2.0; 95% CI = 1.4-2.9; p < 0.001).
In the analysis of global cognitive function, which combined the remaining seven cognitive test scores, a doubling in BC was significantly associated with a decrement of 0.054 SD in cognitive test score in our multivariable-adjusted model (95% CI, −0.103 to −0.006; Table 2), an effect similar to a 1.9-year difference in age in our data.
Assuming that IQ is normally distributed with a standard deviation of 15 points, a doubling of mercury concentration would be associated with a decrement ranging from 0.85 to 2.4 IQ points.
Therefore, the total QALY decrement associated with each SRE was computed by doubling the disutility value resulting from the TTO task Since this study was conducted with a sample from the general population, most participants had a high TTO utility for their own current health (mean = 0.94; SD = 0.09; mode = 0.96 which was the utility for 135 of the 187 participants).
Ventricular ERP was determined at a drive cycle length of 100 ms. Programmed ventricular stimulation, consisting of burst pacing at cycle lengths of 100 ms to 50 ms in decrements of 10 ms, and of programmed stimulation with double and triple extrastimuli at a drive cycle length of 100 ms with a coupling interval ≥30 ms, were performed.
Therefore, the total QALY decrement associated with each SRE can be computed by doubling the disutility value resulting from the current TTO task.
Moreover, for every 0.5 mg/dL decrement in SUA, the risk of adverse renal outcomes (a doubling of serum creatinine or development of ESRD) decreased by 6% [ 96].
We anchored each double-double test with the fittest genotype (say ar) on the left-hand side, and calculated the average fitness decrement, Δ = ar - (as + br)/2, of the two genotypes that appear on the right-hand side of the equation.
