Sentence examples for double changes from inspiring English sources

Enzymes with the double changes at 225 and 274 (mutant G225A-A274F) showed, apart the substantial low Km value for NADPH and its high catalytic efficiency, kinetic parameters relative to coenzymes which were not additive over the single substitutions.

Next, I studied the effect of allowing double changes.

Interestingly, the number of total accessible pathways shows a sharply peaked distribution relative to the number of total double changes, with 83.4% of possible accessible pathways having between 2 and 5 double changes (Figure 2).

I then allow double changes – that is, I allow for direct transitions between haplotypes that are separated by differences at two sites.

Allowing double changes (but not yet back mutations), there are 240 total possible paths with one double mutation, and 90 additional possible paths with two double mutations.

Interestingly, in contrast to the case with neutral mutations, repeatability does not strictly decrease with the relative probability of double mutations, but begins to increase when double changes are at similar probabilities to single changes (Figure 3).

O'Sullivan also makes a double change in his front row.

2.52pm BST 64 min Double change for Fulham.

89 min: Double change for Blackpool: Martinez and Dobbie go off, Bednar and Dicko are on.

A double change followed: Kévin Gameiro and Angel Correa appeared to make good the change, but the rebellion was quashed swiftly.

10.51pm GMT 42nd over: England 80-5 (Root 8, Prior 6) It's a double change for New Zealand.