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Exact(16)
The study design was prospective and double blind with parallel groups.
Ten healthy female subjects and 10 age-matched healthy male subjects participated in the study, which was randomized and double blind with crossover design.
This study was randomized, dose-escalating, and double blind with respect to active vaccine candidate or saline placebo, but not with respect to dose group or mode of administration (IM versus EP).
Thirteen trials were double blind, with masking of both patients and investigators.
RCTs with a placebo control group were double blind with blinding of participants and personnel.
30 31 32 33 34 All the trials were double blind, with adequate allocation concealment (table 2).
Similar(44)
The study was double blinded, with both participants and investigators unaware of treatment assignment until completion of the study.
This study will be double blinded with the assessors, data analysts and a number of investigators (TC, FC and GM) blinded from group allocation.
The other two treatment arms, consisting of patients receiving bedtime Insulin once daily in addition to existing oral medication, were double blinded with glargine controlled by NPH insulin.
All of the included trials were double blinded, with the exception of one trial from the insulin subgroup (15) in which the comparator group received an extra insulin injection and, thus, was only partially blinded.
We planned to include in the initial analysis, trials that met the following criteria: calcium supplementation without any co-supplements; random allocation with secure allocation concealment; and double blinding with placebo.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com