To test this hypothesis, we conducted a prospective double-blind randomized study in ICU patients to assess the impact of enteral administration of Lactobacillus casei rhamnosus strain 35 (Lcr35), a well documented probiotic strain that is manufactured as a pharmaceutical product [ 24, 25], on gastric and respiratory tract colonization/infection by Pseudomonas aeruginosa.
Patients participated in a double blind randomized study comparing effectiveness of taurine versus placebo in reducing morbidity and 1-year mortality in elderly hip fracture patients [5].
Indeed, Rabe et al demonstrated the benefit of roflumilast in COPD patients in a multicenter double blind randomized study of 24 weeks.
A double blind, randomized study of rituximab plus chemotherapy versus chemotherapy alone in aggressive NHL has confirmed these findings [ 29].
12 A double-blind randomized study was performed in 10 men and women with skin type II and III in order to assess the ability of a cream containing LRP-TSW versus the same cream containing demineralized water to protect against ultraviolet B-induced erythema and formation of sunburn cells.
A recent double-blind, randomized study demonstrated that minocycline was effective in the treatment of negative and cognitive symptoms of patients with early-phase schizophrenia [19].
Double-blind randomized study on 32 Wistar rats was performed in order to evaluate the efficacy of proposed GRG gel, by using nerve guide conduits in complete peripheral nerve injury with 15 mm segmental loss.
The aim of this study is to establish this relation in first-degree relatives of gastric cancer patients, who underwent H. pylori eradication in a double blind randomized controlled study for the effect of H. pylori eradication on the morphological changes of gastric mucosa.
One of the first was a double blind randomized placebo controlled study in which 553 women with SUI received placebo, 20 mg duloxetine, 40 mg duloxetine or 80 mg duloxetine for 12 weeks.
The acute effect of PF-04427429 anti-CGRP monoclonal antibody, on attenuation of flare response after capsaicin challenge, used to induce experimental human pain, was studied in a double blind, randomized, placebo-controlled, third-party open, modified cross-over study in male healthy volunteers and using EMLA® cream as positive control [66].
