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A phase 1 double blind randomized controlled dose escalation trial was conducted in Bandiagara, Mali, West Africa, a rural town with intense seasonal transmission of Plasmodium falciparum malaria.
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The study was a double-blind, randomized, controlled, dose escalation phase Ib trial, designed to assess the safety, reactogenicity and immunogenicity of three doses of either 15 or 30 µg of MSP3-LSP adsorbed on aluminum hydroxide in 45 children 12 to 24 months of age randomized into three equal groups.
The study was a double-blind, randomized, controlled, dose escalation phase Ib trial (www.clinicaltrials.gov NCT00452088) designed to assess the safety, reactogenicity and immunogenicity of three injections of either 15 µg or 30 µg of MSP3-LSP adsorbed on aluminum hydroxide in children 12 to 24 months of age.
The first study (PsA-TT-004) was a phase 2, double-blind, randomized, controlled, dose-ranging study to evaluate the safety, immunogenicity, dose response, and schedule response of PsA-TT administered concomitantly with local EPI vaccines in healthy infants.
Design: Nine-week doublindlind, randomized controlled trial.
Double blind randomized controlled trial conducted at the ICU of the Hospital de Clínicas de Porto Alegre, Brazil.
[5] Every large double blind randomized controlled clinical study has the concept of an average patient.
First, the nature of sex reassignment precludes double blind randomized controlled studies of the result.
This is a double blind randomized controlled trial (RCT).
This study is a double blind randomized controlled trial.
We present a double blind randomized controlled design.
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