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In order to preserve the double-blind assignment, treatments were prepared by a third person not being involved in the evaluation of subjects.
They reported that explaining double-blind assignment to volunteers would pose problems for trial recruitment and retention: Community will not accept if we tell like this; even people who accepted [to participate] earlier will now not accept, because they would be afraid that they are being cheated…they would not understand.
Allocation sequence was generated by a statistician in the Medical Center Biostatistics Unit; serial envelopes identifying double-blind treatment assignment to drug A, B or C were prepared by a staff member who did not work on this trial.
All participants, those who administer the therapy and those who assess the outcomes are blinded to group assignment to ensure the double blind design.
Double blind method.
Study Design: Prospective, randomized, double blind study.
Design: prospective double blind, randomised, control study.
Design: Nine-week doublindlind, randomized controlled trial.
Design: Double blind, prospective, placebo-controlled trial.
Blinding, as in "double blind," is a defense against bias.
Design: Double blind RCT.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com