Sentence examples for double affected from inspiring English sources

Serum Hep-1 was decreased in all three hemochromatosis models, being lowest in the double affected mice.

As shown in Figure 5, liver hepcidin-1 mRNA levels (panel A) as well as serum Hep-1 levels (panel B) were decreased in all three hemochromatosis models and lowest in the double affected Hfe/TfR2 y245x mice.

This method was biologically validated by hepcidin assessment in: i) 3 mouse strains (C57Bl/6; DBand and BABL/c) upon stimulation with intravenous iron and LPS, ii) homozygous Hfe knock out, homozygous transferrin receptor 2 (Y245X) mutated mice and double affected mice, and iii) mice treated with a sublethal hepatotoxic dose of paracetamol.

In-line with previous studies showing that defects in the HFE and TfR2 proteins (and their combination) upstream from hepcidin synthesis resulted in low circulating hepcidin levels [22] [27], our 3 mouse hemochromatosis models all showed impaired Hep-1 production, being most prominently present in double affected Hfe/TfR2y245x mice.

"Under the Romney/Ryan budget, interest rates on federal student loans would be allowed to double, affecting Julia and 7.4 million other students," the graphic says when Julia turns 25.

Since then, steel prices have nearly doubled, affecting not only structural steel, but also all metal products, steel railings, pipes, electrical conduits and copper wire.

We found that double standards affected job recommendations and judged suitability of candidates, but not their judged competence.

On the other hand, the structural changes located in the double bond affected much more smoothly the capacity of capturing radicals than the starting molecule, also being obtained derivatives with proximal antioxidant capacity (IC50 = 19.30 μg/mL) to commercial standards such as Trolox (IC50 = 16.00 μg/mL).

The double blow affected Waugh severely; he wrote in his diary in July: "The phrase 'the end of the tether' besets me with unshakeable persistence".

We have examined ABA production in esk1 mutants and the phenotypes of double mutants affected in ABA responses and esk1.

Thus, girls are in double jeopardy, affected by both gender and poverty.