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The dossier is based on the work of the British Joint Intelligence Committee.
The dossier is based on what it calls a reasonableness test: "Any statement by a Labour frontbencher that a voter would believe to be a promise to spend money or raise revenue if Labour are elected is counted as a commitment".
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Mr Osborne's spending dossier was based on an attack on Labour in January 1992 (which was itself a copy of Republican attacks on Michael Dukakis, the Democratic candidate in the 1988 American presidential election).
Clinical data in the dossier were based on a MenA conjugate vaccine that used group A polysaccharide made at SynCo Bio Partners in Amsterdam.
Overall, the GBA decision is based on the manufacturers' dossier and submitted data, the IQWiG evaluation, as well as the results of the public hearing as part of the commenting procedure.
The G-BA decision is based on the manufacturers' dossier, IQWiG evaluation, as well as the results of a public hearing.
A nonquantitative breadth score is displayed on each dossier and EPA symbol (see Fig. 2) and is based on the value of NE > 15 as follows: 1 = MIN, 2 3 = MOD, 4 5 = EXT, 6 8 = EXE.
A nonquantitative Depth label is displayed on each dossier and EPA symbol (see Fig. 2) and is based on the quantitative depth score D as follows: 1−10 = minimal (MIN), 11 25 = moderate (MOD), 26 45 = extensive (EXT), 46 60 = exemplary (EXE).
** Turning to the dossier's executive summary, which contained a bald assertion of the forty-five-minutes claim, the analyst went on: **{:.break one} ** This is based on a single source.
In a note forwarded to the Cabinet Office, one analyst pointed out that the forty-five-minutes claim was "rather strong since it is based on a single source" and proposed amending the dossier to say "intelligence suggests" it was true.
A ruling on additional benefit for a specific compound by the GBA (appraisal) is based on the overall assessment of the evidence presented in the dossier for effects on mortality, morbidity, and HRQoL.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com