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The ionized calcemia dosing through the filter ("post-filter" ionized-calcemia) is used to monitor the technique efficacy, with a target of 0.25 0.35 mmol/L showing a good filter anticoagulation.
The in vivo half-life of the construct was tuned to support nightly dosing through design and testing in cynomolgus monkeys.
In contrast, the ASCO and NCCN guidelines recommend dexamethasone dosing through Day 3 or 4 in the AC setting.
In both periods, eligible subjects resided in the clinical unit for at least 12 h prior to dosing through 36 h following dosing.
From the 8th day of dosing through the 11th day of dosing, mean BW of animals receiving 30 mg PFOA/kg/day (recovery and constant) was reduced by approximately 8% (p < 0.05) relative to BW of animals receiving vehicle.
From the 8th day of dosing through the end of the dosing period, mean BW of animals drinking 30 mg PFOA/kg/day was reduced by 6 15% (p < 0.05) relative to BW of animals drinking vehicle water.
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And Animas, a division of Johnson & Johnson, makes programmable pumps the size of a cellphone that administer insulin doses through a tiny implantable catheter.
All animals were dosed through oral gavage (per os).
The latter way of dosing could be realised, e.g., in a membrane reactor where one or several reactants can be dosed through a porous reactor wall.
Young, male Wistar rats (100 120 g) were divided into four groups of five or six animals each and were dosed, through water, with 10% ethanol (vol./vol)./vol
Daily BaPeq exposure doses through ingestion and dermal adsorption as well as their carcinogenic risks were calculated via both deterministic and probabilistic approaches.
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