Sentence examples for dosing strategy from inspiring English sources

Although this dosing strategy appears efficacious, it is based on clinical trials rather than pharmacokinetic (PK pharmacodynamic (PD) assessments.

This study explores the drug linezolid through stochastic modeling and optimal dosing strategy.

These distinct treatment responses support the histopathological findings on CD4+ T cells observed with the prophylactic dosing strategy.

Characterization of these pharmacodynamic properties for a new drug in development can help direct the design of the best dose and dosing strategy for clinical trials.

STUDY OBJECTIVE: To evaluate the pharmacokinetics of gentamicin in neonates with hypoxic ischemic encephalopathy (HIE) receiving hypothermia and to identify an empiric gentamicin dosing strategy in this population that optimizes achievement of target peak and trough concentrations.

Clinical trials for the evaluation of these neurosteroids face challenges in terms of experimental design, dosing strategy, data analysis, and interpretation.

The most promising parameters for a large NOX reduction and a low fuel penalty have been applied in the dosing strategy and tested in an ETC.

Pharmacokinetic analysis generated an optimal dosing strategy to achieve effective TP10 levels for 24 hours after CPB.

In the rat PTOA model, our IL-1 ra dosing strategy ameliorated synovitis but did not alter the extent of cartilage degeneration.

INTRODUCTION: While it is common practice that hypnotics are used on a non-nightly basis, few investigations have been undertaken to evaluate the efficacy of the intermittent dosing strategy.

Inhaled carbon monoxide (CO) gas has therapeutic potential for patients with acute respiratory distress syndrome if a safe, evidence-based dosing strategy and a ventilator-compatible CO delivery system can be developed.