Sentence examples for dosing schemes from inspiring English sources

Then, the predicted quality indices are fed back to the optimizations of the first and second proportionings to find feasible optimal dosing schemes.

This is the first reported study in man, at a resolving power of 30 μm, of drug localization within organ compartments using normal clinical dosing schemes and standardized laboratory measurement.

This is the first reported study in man, at a resolving power of 30 μm, of drug localization within organ microenvironments using normal clinical dosing schemes and standardized laboratory measurement [35].

After validation of the computational models, we assessed resulting internal exposures that corresponded to repeated dosing schemes within each species (1, 5, 10, 50, 100 mg/kg(bw)/day).

The individual steady-state values reached after different dosing schemes give rise to a human:rat steady-state-based margin of exposure (MOE) ratio range of 0.33 0.44 and a human:rat AUC-based MOE range range of 0.33 0.37 for pharmacokinetic extrapolation with respect to the dietary exposure schemes assessed.

In this study, a metabolomic fingerprint of NAFLD induced in HepaRG® cells at four dosing schemes by a reference toxicant, sodium valproate (NaVPA), was obtained using liquid-liquid extraction followed by liquid chromatography and accurate mass mass spectrometry (LC AM/MS).

Not surprisingly, the two companies argue over which dosing scheme is better.

In the intelligent integrated optimization level, an intelligent integrated optimizer (IIO) produces an optimal dosing scheme.

This can have significant consequences on study design (both pre-clinical and clinical), in particular on dose selection, dosing scheme, and sampling times.

The time horizon was calculated for each claim, for which the prescription should suffice, assuming that the treatment was initiated with the recommended dosing scheme.

This dosing scheme was selected based on a previous pharmacokinetic study using a single 10 mg/kg subcutaneous dose in swine.