Sentence examples for dosing irregularities from inspiring English sources

The relationship between adherence and outcome is complex, as the pharmacodynamic and pharmacokinetic properties of the each drug and drug formulation directly impacts the effects of dosing irregularities.

HIV RNA blips do not appear to be associated with decreased antiretroviral adherence or dose-timing irregularities 5– 9. HIV RNA blips > 500 HIV-1 RNA copies/ml have been associated with subsequent virological rebound 15 and with a dampened CD4 cell count increase 16, 17 and thus could affect outcomes in coinfection.

We allowed for a gap of up to four weeks between the end of the interval of the latest dose and the date of the subsequent dose being administered to account for irregularities in the dosage interval.

At low doses, barium ions act as a muscle stimulant, whereas higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, dyspnea and paralysis.

Manufacturing irregularities, improper drug reconstitution, and inappropriate dosing were ruled out as possible causes of PDSS.

The data were expressed as overall compliance (OC), defined as the observed number of bottle openings as a percentage of the prescribed number of doses, and as two indices representing daily and hourly irregularities in the times of opening.

There were irregularities in the way Mr Bennett was prescribed heavy doses of three anti-psychotic drugs.

However, two subjects were excluded because of serious irregularities: one received the same treatment in both periods and the other provided dates of dosing in the second treatment period that were earlier than those in the first treatment period.

When pregnant mice are exposed to an asymptomatic dose of DA on GD13, the postnatal offspring show no evidence of spontaneous seizures, yet demonstrate increasing irregularities in electroencephalogram recordings in postnatal life (Dakshinamurti et al. 1993).

"We found no irregularities.

Yet irregularities are widespread.